Aggregation of Polypeptide-Based Amphiphiles in Water

Aggregation of p-Sulfonatocalixarene-Based Amphiphiles and Supra-Amphiphiles

p-Sulfonatocalixarenes are a special class of water soluble macrocyclic molecules made of 4-hydroxybenzenesulfonate units linked by methylene bridges. One of the main features of these compounds relies on their ability to form inclusion complexes with cationic and neutral species. This feature, together with their water solubility and apparent biological compatibility, had enabled them to emerg...

Aggregation of Amphiphiles in Ternary Mixtures

We present an improved version of an earlier Larson-type model of amphiphiles. Detailed descriptions of the algorithms are given and some situations where care must be taken are pointed out We use the model to calculate the condensation transition temperature of amphiphiles in a ternary mixture. The concentration percolation threshold and percolation critical exponent of arnphiphile clusters at...

H-aggregation of azobenzene-substituted amphiphiles in vesicular membranes.

Photochemical switching has been studied of double-tailed phosphate amphiphiles containing azobenzene units in both tails in aqueous vesicular dispersions and in mixed vesicular systems with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC). Since the ease of switching depends on the strength of the bilayer packing, particular emphasis has been placed on the occurrence of H-aggregation in the hyd...

Aggregation behavior of giant amphiphiles prepared by cofactor reconstitution.

We report on biohybrid surfactants, termed "giant amphiphiles", in which a protein or an enzyme acts as the polar head group and a synthetic polymer as the apolar tail. It is demonstrated that the modification of horseradish peroxidase (HRP) and myoglobin (Mb) with an apolar polymer chain through the cofactor reconstitution method yields giant amphiphiles that form spherical aggregates (vesicle...

Peptide based amphiphiles.